![]() The GRADE (Grading of Recommendations Assessment, Development and Evaluation) system was used to grade the evidence and guide recommendations. The target audience for this guideline includes all clinicians involved in the management of insomnia, and the target patient population includes adults with chronic insomnia disorder. The guideline is based on a systematic review of relevant meta-analyses published till June 2016. This European guideline for the diagnosis and treatment of insomnia was developed by a task force of the European Sleep Research Society, with the aim of providing clinical recommendations for the management of adult patients with insomnia. The guideline is based on a systematic review of relevant meta-analyses published till. read more read lessĪbstract: This European guideline for the diagnosis and treatment of insomnia was developed by a task force of the European Sleep Research Society, with the aim of providing clinical recommendations for the management of adult patients with insomnia. These adaptive changes are hypothesized to restrict brain operational capacity and to persist for several days after normal sleep duration is restored, delaying recovery. In mild to moderate sleep restriction this adaptation is sufficient to stabilize performance, although at a reduced level. These results suggest that the brain adapts to chronic sleep restriction. Performance in the 9-h group remained at baseline levels during the recovery phase. Speed and lapses in the 3-h group recovered rapidly following the first night of recovery sleep however, recovery was incomplete with speed and lapses stabilizing at a level comparable with the 7- and 5-h groups. During recovery, PVT speed in the 7- and 5-h groups (and lapses in the 5-h group) remained at the stable, but reduced levels seen during the last days of the experimental phase, with no evidence of recovery. In the 9-h group, speed and lapses remained at baseline levels. ![]() In the 7- and 5-h groups speed initially declined, then appeared to stabilize at a reduced level lapses were increased only in the 5-h group. In the 3-h group, speed (mean and fastest 10% of responses) on the psychomotor vigilance task (PVT) declined, and PVT lapses (reaction times greater than 500 ms) increased steadily across the 7 days of sleep restriction. Sixty-six normal volunteers spent either 3 (n = 18), 5 (n= 16), 7 (n = 16), or 9 h (n = 16) daily time in bed (TIB) for 7 days (restriction/augmentation) followed by 3 days with 8 h daily TIB (recovery). Daytime performance changes were examined during chronic sleep restriction or augmentation and following subsequent recovery sleep. ![]() Sixty-six normal volunteers spent either 3 (n = 18), 5 (n= 16), 7 (n = 16), or 9 h (n = 16) daily time in bed (TIB) for 7 days (restriction/augmentation) followed by 3 days with 8 h daily TIB (re. Abstract: Daytime performance changes were examined during chronic sleep restriction or augmentation and following subsequent recovery sleep.
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